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Life SciencesCell BiologyMolecular BiologyApoptosisCell CycleCell DivisionCell-cycle ArrestG1 PhaseG2 PhaseMitosisMitotic EntryMitotic SpindleCell Division ArrestMitosis ArrestS-phase Arrest
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Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7
Ingrid E. Wertz, Saritha Kusam, Cynthia Lam et al. · Nature · 2011 · 810 citations
SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction
Hiroyuki Inuzuka, Shavali Shaik, Ichiro Onoyama et al. · Nature · 2011 · 629 citations · Full text
Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival
Martin Schwickart, Xiaodong Huang, Jennie R. Lill et al. · Nature · 2009 · 620 citations
Medicine, Cancer Biology, Oncology +13