Length-dependent conformational transitions of polyglutamine repeats as molecular origin of fibril initiation

Glutamine repeats as polar zippers: their possible role in inherited neurodegenerative diseases.

M. F. Perutz, T. Johnson, Masashi Suzuki et al. · Proceedings of the National Academy of Sciences · 1994 · 1.1K citations · Full text

Protein Assembly, Molecular Biology, Glutamine Repeats +21

Use of the glass electrode in deuterium oxide and the relation between the standardized pD (paD) scale and the operational pH in heavy water

A. K. Covington, Maya Paabo, R. A. Robinson et al. · Analytical Chemistry · 1968 · 651 citations

Environmental Electrochemistry, Chemical Engineering, Chemical Measurement +15

Huntington's disease age-of-onset linked to polyglutamine aggregation nucleation

Songming Chen, Frank A. Ferrone, Ronald Wetzel · Proceedings of the National Academy of Sciences · 2002 · 524 citations · Full text

Protein Assembly, Genetics, Molecular Biology +18

Amyloid fibers are water-filled nanotubes

M. F. Perutz, J.T. Finch, John Berriman et al. · Proceedings of the National Academy of Sciences · 2002 · 506 citations · Full text

Polyglutamine aggregation behavior in vitro supports a recruitment mechanism of cytotoxicity

Songming Chen, Valérie Berthelier, Wen‐Bin Yang et al. · Journal of Molecular Biology · 2001 · 340 citations

Medicine, Cell Death, Neuropharmacology +7