Concepedia

Fibril Elongation

Fibril Elongation is a molecular process in protein aggregation wherein misfolded proteins sequentially add to the ends of existing amyloid fibrils, extending their length through the templated conversion of soluble monomers into the fibrillar conformation.

372

Publications

25.3K

Citations

1.5K

Authors

527

Institutions

Publications per year

2017–2026

102

Parents

Publications

372

Effect of Environmental Factors on the Kinetics of Insulin Fibril Formation:  Elucidation of the Molecular Mechanism

Liza Nielsen, Alisa C. Coats, Jens Brange et al. · Biochemistry · 2001 · 1.2K citations

, , +13

On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants.

Aleksey Lomakin, Doo Soo Chung, George B. Benedek et al. · Proceedings of the National Academy of Sciences · 1996 · 783 citations

, , +17

Cryo-EM structure of alpha-synuclein fibrils

Ricardo Guerrero-Ferreira, Nicholas M. I. Taylor, Daniel Mona et al. · eLife · 2018 · 598 citations · Full text

, , +17

Kinetic theory of fibrillogenesis of amyloid β-protein

Aleksey Lomakin, David B. Teplow, Daniel A. Kirschner et al. · Proceedings of the National Academy of Sciences · 1997 · 529 citations · Full text

, , +17

Assembly of Aβ Amyloid Protofibrils:  An in Vitro Model for a Possible Early Event in Alzheimer's Disease

James D. Harper, Stanislaus S. Wong, Charles M. Lieber et al. · Biochemistry · 1999 · 454 citations

, , +17

1–5 of 372

Authors

1.5K

  1. AK
    Alexander K. Buell

    University of Cambridge, United Kingdom

    12 publications · 1.1K citations

    12

    h-index

  2. CM
    Christopher M. Dobson

    University of Cambridge, United Kingdom

    9 publications · 792 citations

    9

    h-index

  3. DE
    Daniel E. Otzen

    Aarhus University, Denmark

    8 publications · 573 citations

    8

    h-index

  4. DB
    David B. Teplow

    University of California, Los Angeles, United States

    7 publications · 2.3K citations

    7

    h-index

  5. TP
    Tuomas P. J. Knowles

    University of Cambridge, United Kingdom

    7 publications · 763 citations

    7

    h-index

1–5 of 1.5K

Institutions

527

  1. University of Cambridge

    Cambridge, United Kingdom

    15 h-index

    75 publications

    6.7K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    14 h-index

    35 publications

    2.4K citations

  3. Aarhus University

    Aarhus, Denmark

    11 h-index

    41 publications

    3.9K citations

  4. Harvard University

    Cambridge, United States

    9 h-index

    20 publications

    5.4K citations

  5. Massachusetts Institute of Technology

    Cambridge, United States

    9 h-index

    34 publications

    11.1K citations

  6. Heinrich Heine University Düsseldorf

    Düsseldorf, Germany

    9 h-index

    32 publications

    1.4K citations

  7. University of California, Los Angeles

    Los Angeles, United States

    7 h-index

    47 publications

    5.4K citations

  8. Brigham and Women's Hospital

    Boston, United States

    7 h-index

    22 publications

    8.7K citations

1–8 of 527

Venues

  1. Journal of Biological Chemistry

    JBC · 22 publications · 2.5K citations

    20

    h-index

  2. Journal of Molecular Biology

    JMB · 20 publications · 882 citations

    16

    h-index

  3. Biochemistry

    15 publications · 2.6K citations

    13

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 12 publications · 2.8K citations

    12

    h-index

  5. Journal of the American Chemical Society

    JACS · 9 publications · 1.1K citations

    9

    h-index

1–5