Neprilysin-2 Is an Important β-Amyloid Degrading Enzyme

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Triple-Transgenic Model of Alzheimer's Disease with Plaques and Tangles

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Alzheimer's Disease, Dementia, Degenerative Disease +5

Forecasting the global burden of Alzheimer's disease

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Metabolic Regulation of Brain Aβ by Neprilysin

Nobuhisa Iwata, Satoshi Tsubuki, Yoshie Takaki et al. · Science · 2001 · 944 citations

Aging, Neurochemical Biomarkers, Amyloid Beta Peptide +19

Identification of the major Aβ1–42-degrading catabolic pathway in brain parenchyma: Suppression leads to biochemical and pathological deposition

Nobuhisa Iwata, Satoshi Tsubuki, Yoshie Takaki et al. · Nature Medicine · 2000 · 856 citations

Neurodegenerative Diseases, Synaptic Signaling, Degenerative Pathology +9