Regulation of the proapoptotic BH3-only protein BIM by glucocorticoids, survival signals and proteasome in chronic lymphocytic leukemia cells

Differential Targeting of Prosurvival Bcl-2 Proteins by Their BH3-Only Ligands Allows Complementary Apoptotic Function

Lin Chen, Simon N. Willis, Andrew H. Wei et al. · Molecular Cell · 2005 · 1.8K citations · Full text

Medicine, Apoptosis, Immunology +7

Proapoptotic Bcl-2 Relative Bim Required for Certain Apoptotic Responses, Leukocyte Homeostasis, and to Preclude Autoimmunity

Philippe Bouillet, Donald Metcalf, David C.S. Huang et al. · Science · 1999 · 1.5K citations

Clinical Immunology, Certain Apoptotic Responses, Preclude Autoimmunity +18

Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members

Michael Certo, Victoria Del Gaizo Moore, Mari Nishino et al. · Cancer Cell · 2006 · 1.2K citations · Full text

Death Signals, Mitophagy, Cellular Addiction +10

Bim: a novel member of the Bcl-2 family that promotes apoptosis

Liam O’Connor · The EMBO Journal · 1998 · 1.2K citations · Full text

Cell Regulation, Apoptosis, Cell Death +6

Expression of the pro-apoptotic Bcl-2 family member Bim is regulated by the forkhead transcription factor FKHR-L1

Pascale F. Dijkers, René H. Medema, Jan‐Willem J. Lammers et al. · Current Biology · 2000 · 965 citations · Full text

Cell Regulation, Genetics, Apoptosis +7