On-line solid phase synthesis of oligonucleotide-peptide hybrids using silica supports

Deoxynucleoside phosphoramidites—A new class of key intermediates for deoxypolynucleotide synthesis

Serge L. Beaucage, Marvin H. Caruthers · Tetrahedron Letters · 1981 · 2K citations

Biosynthesis, Bioorganic Chemistry, Nucleic Acid Chemistry +6

Synthesis of deoxyoligonucleotides on a polymer support

Mark D. Matteucci, M. H. CARUTHERS · Journal of the American Chemical Society · 1981 · 874 citations

Dna Nanotechnology, Molecular Characterization, Molecular Sciences +15

Specific antiviral activity of a poly(L-lysine)-conjugated oligodeoxyribonucleotide sequence complementary to vesicular stomatitis virus N protein mRNA initiation site.

Marc Lemaître, Bernard Bayard, Bernard Lebleu · Proceedings of the National Academy of Sciences · 1987 · 328 citations · Full text

Viral Replication, Viral Polymerase Structure, Synthetic Virology +21

Short modified antisense oligonucleotides directed against Ha-ras point mutation induce selective cleavage of the mRNA and inhibit T24 cells proliferation.

Tula Saison‐Behmoaras, Bruno Tocqué, Ignacio Antonio Gemio del Rey et al. · The EMBO Journal · 1991 · 203 citations · Full text

Selective Cleavage, Immunology, Oligonucleotide +7

Biological activity of oligonucleotide-poly(L-lysine) conjugates: mechanism of cell uptake

Jean Paul Leonetti, Geneviève Degols, Bernard Lebleu · Bioconjugate Chemistry · 1990 · 162 citations