Tula Saison‐Behmoaras

Short modified antisense oligonucleotides directed against Ha‐ras point mutation induce selective cleavage of the mRNA and inhibit T24 cells proliferation.

Tula Saison‐Behmoaras, Bruno Tocqué, Ignacio Antonio Gemio del Rey et al. · The EMBO Journal · 1991 · 203 citations · Full text

Medicine, Molecular Biology, Oncology +15

Sequence-specific intercalating agents: intercalation at specific sequences on duplex DNA via major groove recognition by oligonucleotide-intercalator conjugates.

Jian‐Sheng Sun, Jean‐Christophe François, Thérèse Montenay-Garestier et al. · Proceedings of the National Academy of Sciences · 1989 · 181 citations · Full text

Life Sciences, Biophysics, Molecular Biology +16

Antisense oligonucleotides adsorbed to polyalkylcyanoacrylate nanoparticles specifically inhibit mutated Ha-ras-mediated cell proliferation and tumorigenicity in nude mice.

G Schwab, Christine Chavany, Gérard Goubin et al. · Proceedings of the National Academy of Sciences · 1994 · 169 citations

Medicine, Molecular Biology, Oncology +17

A triple helix-forming oligonucleotide-intercalator conjugate acts as a transcriptional repressor via inhibition of NF kappa B binding to interleukin-2 receptor alpha-regulatory sequence.

Mikhaïl Grigoriev, Danièle Praseuth, Philippe Robin et al. · Journal of Biological Chemistry · 1992 · 168 citations · Full text

Life Sciences, Chemical Biology, Molecular Biology +14

Sequence-specific recognition and cleavage of duplex DNA via triple-helix formation by oligonucleotides covalently linked to a phenanthroline-copper chelate.

Jean‐Christophe François, Tula Saison‐Behmoaras, Claudette Barbier et al. · Proceedings of the National Academy of Sciences · 1989 · 149 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13