Concepedia

Synthesis of pyrrolo[2,1-c][1,4]benzodiazepines via reductive cyclization of ω-azido carbonyl compounds by TMSI: an efficient preparation of antibiotic DC-81 and its dimers

Ahmed Kamal, E. Laxman, N. Laxman, N. Venugopal Rao

Bioorganic & Medicinal Chemistry Letters · 2000 · 29 citations · 22 references

DOI

Concepts

References

22

Rational design of a highly efficient irreversible DNA interstrand cross-linking agent based on the pyrrolobenzodiazepine ring system

D. Subhas Bose, Andrew S. Thompson, Jingshan Ching et al. · Journal of the American Chemical Society · 1992 · 136 citations

, , +22

Covalent binding of antitumor antibiotics in the minor groove of DNA. Mechanism of action of CC-1065 and the pyrrolo(1,4)benzodiazepines

Laurence H. Hurley, Donald R. VanDevanter · Accounts of Chemical Research · 1986 · 124 citations

, , +20

Synthesis of Sequence-Selective C8-Linked Pyrrolo[2,1-<i>c</i>][1,4]benzodiazepine DNA Interstrand Cross-Linking Agents

David E. Thurston, D. Subhas Bose, Andrew S. Thompson et al. · The Journal of Organic Chemistry · 1996 · 114 citations

, , +11

Total synthesis of anthramycin

W. Leimgruber, Andrew D. Batcho, Rafał Czajkowski · Journal of the American Chemical Society · 1968 · 91 citations

, , +18

Structure of a Covalent DNA Minor Groove Adduct with a Pyrrolobenzodiazepine Dimer: Evidence for Sequence-Specific Interstrand Crosslinking

Terence C. Jenkins, Laurence H. Hurley, Stephen Neidle et al. · Journal of Medicinal Chemistry · 1994 · 90 citations