Stereoselective synthesis of (−)-(1R,2S)-2-aminocyclobutane-1-carboxylic acid, a conformationally constrained β-amino acid

β‐Peptides: Synthesis by <i>Arndt‐Eistert</i> homologation with concomitant peptide coupling. Structure determination by NMR and CD spectroscopy and by X‐ray crystallography. Helical secondary structure of a β‐hexapeptide in solution and its stability towards pepsin

Dieter Seebàch, Mark Overhand, Florian N. M. Kühnle et al. · Helvetica Chimica Acta · 1996 · 719 citations

Life Sciences, Biochemistry, Protein Biochemistry +16

β-Peptide Foldamers:  Robust Helix Formation in a New Family of β-Amino Acid Oligomers

Daniel H. Appella, Laurie A. Christianson, Isabella L. Karle et al. · Journal of the American Chemical Society · 1996 · 686 citations

Life Sciences, Biochemistry, Biophysics +13

Enzymes in organic synthesis. 39. Preparations of chiral cyclic acid-esters and bicyclic lactones via stereoselective pig liver esterase catalyzed hydrolyses of cyclic meso diesters

Gabriele Sabbioni, J. Bryan Jones · The Journal of Organic Chemistry · 1987 · 99 citations

Natural Sciences, Biochemistry, Chemistry +6

3,5-Dimethylphenylcarbamates of amylose, chitosan and cellulose bonded on silica gel

Pilar Franco, Antonio Senso, Cristina Minguillón et al. · Journal of Chromatography A · 1998 · 83 citations

Natural Sciences, Chemistry, Materials Science +12

Betas are brought into the fold

Brent L. Iverson · Nature · 1997 · 80 citations · Full text

Life Sciences, Cell Biology, Protein Folding +7