Stat3 as a Therapeutic Target for the Treatment of Psoriasis: A Clinical Feasibility Study with STA-21, a Stat3 Inhibitor

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

J. Daniel, Jonathan Sherlock, Yi Chen et al. · Nature · 2003 · 2.9K citations

Inflammation, Cytokine, Psychoneuroimmunology +14

Development, cytokine profile and function of human interleukin 17–producing helper T cells

Nicholas J. Wilson, Katia Boniface, Jason R. Chan et al. · Nature Immunology · 2007 · 2K citations

Inflammation, Cytokine, Immune Cell Development +10

Interleukin-22, a TH17 cytokine, mediates IL-23-induced dermal inflammation and acanthosis

Yan Zheng, Dimitry M. Danilenko, Patricia Valdez et al. · Nature · 2006 · 1.8K citations

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Divergent Pro- and Antiinflammatory Roles for IL-23 and IL-12 in Joint Autoimmune Inflammation

Craig A. Murphy, Claire L. Langrish, Yi Chen et al. · The Journal of Experimental Medicine · 2003 · 1.6K citations · Full text

IL-23 is essential for T cell–mediated colitis and promotes inflammation via IL-17 and IL-6

David Yen, Jeanne Cheung, Heleen Scheerens et al. · Journal of Clinical Investigation · 2006 · 1.5K citations · Full text

Chronic Inflammatory Diseases, Immunology, Immune Regulation +17