Concepedia

J-104129, a novel muscarinic M3 receptor antagonist with high selectivity for M3 over M2 receptors

Morihiro Mitsuya, Toshiaki Mase, Yoshimi Tsuchiya, Kumiko Kawakami, Hiromi Hattori, Kensuke Kobayashi, Yoshio Ogino, Toru Fujikawa, Akio Satoh, Toshifumi Kimura,

Bioorganic & Medicinal Chemistry · 1999 · 49 citations · 27 references

DOI

Concepts

References

27

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.9K citations

, , +14

Identification of a Family of Muscarinic Acetylcholine Receptor Genes

Tom I. Bonner, Noel J. Buckley, Alice C. Young et al. · Science · 1987 · 1.4K citations

, , +14

Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor

Tai Kubo, Kazuhiko Fukuda, Atsushi Mikami et al. · Nature · 1986 · 914 citations

, , +14

Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes

Tom I. Bonner, Alice C. Young, Mark R. Bran et al. · Neuron · 1988 · 791 citations · Full text

, , +10

Distinct primary structures, ligand‐binding properties and tissue‐specific expression of four human muscarinic acetylcholine receptors.

E G Peralta, Avi Ashkenazi, John Winslow et al. · The EMBO Journal · 1987 · 765 citations · Full text

, , +15