J-104129, a novel muscarinic M3 receptor antagonist with high selectivity for M3 over M2 receptors

Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

Yung-Chi Cheng, William H. Prusoff · Biochemical Pharmacology · 1973 · 12.8K citations

Cent Inhibition, Inhibitory Activity, Biochemistry +8

Identification of a Family of Muscarinic Acetylcholine Receptor Genes

Tom I. Bonner, Noel J. Buckley, Alice C. Young et al. · Science · 1987 · 1.4K citations

Molecular Physiology, Medicine, Genetics +13

Cloning, sequencing and expression of complementary DNA encoding the muscarinic acetylcholine receptor

Tai Kubo, Kazuhiko Fukuda, Atsushi Mikami et al. · Nature · 1986 · 914 citations

Molecular Pharmacology, Medicine, Genetics +8

Cloning and expression of the human and rat m5 muscarinic acetylcholine receptor genes

Tom I. Bonner, Alice C. Young, Mark R. Bran et al. · Neuron · 1988 · 791 citations · Full text

Molecular Pharmacology, Molecular Physiology, Signal Transduction +8

Distinct primary structures, ligand-binding properties and tissue-specific expression of four human muscarinic acetylcholine receptors.

E G Peralta, Avi Ashkenazi, John Winslow et al. · The EMBO Journal · 1987 · 764 citations · Full text

Molecular Pharmacology, Biochemistry, Distinct Primary Structures +9