In vivo effects by estrone sulfate on the central nervous system-senile dementia (alzheimer's type)

Honjo Hideo, Yoshio Ogino, Kazuo Naitoh, +9

Journal of Steroid Biochemistry

Alzheimer's DiseaseMedicineDementiaVivo EffectsEstrone Sulfate +10

Thrombin is a regulator of astrocytic endothelin-1

Hannelore Ehrenreich, Tommaso Costa, Kathleen A. Clouse, +4

Brain Research

ThrombosisMolecular NeuroscienceMolecular PhysiologyPhysiologyAstrocytic Endothelin-1 +7

Estrone sulfate and sulfatase activity in human breast cancer and endometrial cancer

Kazuo Naitoh, Hideo Honjo, Takara Yamamoto, +4

Journal of Steroid Biochemistry

Breast OncologyBiochemistryGynecologyEstrone SulfateBreast Cancer +7

Discovery of novel 2-(pyridine-2-yl)-1H-benzimidazole derivatives as potent glucokinase activators

Makoto Ishikawa, Katsumasa Nonoshita, Yoshio Ogino, +10

Bioorganic & Medicinal Chemistry Letters

Medicinal ChemistryBioorganic ChemistryNatural SciencesMedicineDrug Development +5

J-104129, a novel muscarinic M3 receptor antagonist with high selectivity for M3 over M2 receptors

Morihiro Mitsuya, Toshiaki Mase, Yoshimi Tsuchiya, +10

Bioorganic & Medicinal Chemistry

BiochemistryFunctional SelectivityMedicinePhysiologyMechanism Of Action +6

A Potent, Long-Acting, Orally Active (2<i>R</i>)-2-[(1<i>R</i>)-3,3-Difluorocyclopentyl]-2-hydroxy-2-phenylacetamide:  A Novel Muscarinic M₃ Receptor Antagonist with High Selectivity for M₃ over M₂ Receptors

Morihiro Mitsuya, Kensuke Kobayashi, Kumiko Kawakami, +11

Journal of Medicinal Chemistry

Molecular PharmacologyMedicinal ChemistryPharmaceutical ChemistryBiochemistryFunctional Selectivity +13

Design, syntheses, and structure–activity relationships of novel NPY Y5 receptor antagonists: 2-{3-Oxospiro[isobenzofuran-1(3H),4′-piperidin]-1′-yl}benzimidazole derivatives

Yoshio Ogino, Norikazu Ohtake, Yoshikazu Nagae, +13

Bioorganic & Medicinal Chemistry Letters

Molecular PharmacologyMedicinal ChemistryDrug TargetBenzimidazole DerivativesMedicine +4

Pituitary Somatotroph Adenoma Producing Growth Hormone (GH)-Releasing Hormone (GHRH) with an Elevated Plasma GHRH Concentration: A Model Case for Autocrine and Paracrine Regulation of GH Secretion by GHRH1

Akira Matsuno, Hideki Katakami, Naoko Sanno, +5

The Journal of Clinical Endocrinology & Metabolism

Human GrowthPathologyReproductive EndocrinologyPituitary GlandPituitary Disease +14

Direct evidence for two distinct G proteins coupling with thrombin receptors in human neuroblastoma SH-EP cells

Yoshio Ogino, KOSHI TANAKA, N Shimizu

European Journal of Pharmacology

Distinct GThrombin ReceptorsSignal TransductionMolecular PhysiologyG Protein-coupled Receptor +7

Effects of endothelin-1 on Ca2+ signaling and secretion in parathyroid cells

Yoshio Fujii, Melanija Tomić, Stanko S. Stojilković, +4

Journal of Bone and Mineral Research