Concepedia

Discovery, synthesis, and structure–activity relationship of 6-aminomethyl-7,8-dihydronaphthalenes as human melanin-concentrating hormone receptor 1 antagonists

Makoto Kamata, Toshiro Yamashita, Toshihiro Imaeda, Toshio Tanaka, Jun Terauchi, Maki Miyamoto, Taiichi Ora, Michiko Tawada, Satoshi Endo, Shiro Takekawa,

Bioorganic & Medicinal Chemistry · 2011 · 10 citations · 25 references

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25

Development and validation of a genetic algorithm for flexible docking 1 1Edited by F. E. Cohen

Gareth Jones, Peter Willett, Robert C. Glen et al. · Journal of Molecular Biology · 1997 · 6.6K citations

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Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor

Krzysztof Palczewski, Takashi Kumasaka, Tetsuya Hori et al. · Science · 2000 · 5.6K citations

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Molecular recognition of receptor sites using a genetic algorithm with a description of desolvation

Gareth Jones, Peter Willett, Robert C. Glen · Journal of Molecular Biology · 1995 · 1.5K citations

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A role for melanin-concentrating hormone in the central regulation of feeding behaviour

Daqing Qu, David S. Ludwig, Steen Gammeltoft et al. · Nature · 1996 · 1.3K citations

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Mice lacking melanin-concentrating hormone are hypophagic and lean

Masako Shimada, Nicholas A. Tritos, Bradford B. Lowell et al. · Nature · 1998 · 1.2K citations

, , +4