Jun Terauchi

T-226296: a novel, orally active and selective melanin-concentrating hormone receptor antagonist

Shiro Takekawa, Asano Asami, Yuji Ishihara et al. · European Journal of Pharmacology · 2002 · 201 citations · Full text

Functional Selectivity, Medicine, Hormonal Receptor +7

A Noncompetitive BACE1 Inhibitor TAK-070 Ameliorates Aβ Pathology and Behavioral Deficits in a Mouse Model of Alzheimer's Disease

Hiroaki Fukumoto, Hideki Takahashi, Naoki Tarui et al. · Journal of Neuroscience · 2010 · 127 citations · Full text

Neurochemical Biomarkers, Synaptic Signaling, Neuroinflammation +20

N-Allylation of anilides with chiral palladium catalysts: the first catalytic asymmetric synthesis of axially chiral anilides

Jun Terauchi, Dennis P. Curran · Tetrahedron Asymmetry · 2003 · 110 citations

Chemical Engineering, Engineering, Chiral Anilides +8

Discovery of Novel, Highly Potent, and Selective Quinazoline-2-carboxamide-Based Matrix Metalloproteinase (MMP)-13 Inhibitors without a Zinc Binding Group Using a Structure-Based Design Approach

Hiroshi Nara, Kenjiro Sato, Takako Naito et al. · Journal of Medicinal Chemistry · 2014 · 57 citations · Full text

Zinc Binding Group, Chemical Biology, Pharmaceutical Chemistry +20

Discovery of Novel, Highly Potent, and Selective Matrix Metalloproteinase (MMP)-13 Inhibitors with a 1,2,4-Triazol-3-yl Moiety as a Zinc Binding Group Using a Structure-Based Design Approach

Hiroshi Nara, Akira Kaieda, Kenjiro Sato et al. · Journal of Medicinal Chemistry · 2016 · 55 citations · Full text