Naoki Tarui

Discovery of a Novel Pyrrole Derivative 1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1<i>H</i>-pyrrol-3-yl]-<i>N</i>-methylmethanamine Fumarate (TAK-438) as a Potassium-Competitive Acid Blocker (P-CAB)

Yasuyoshi Arikawa, Haruyuki Nishida, Osamu Kurasawa et al. · Journal of Medicinal Chemistry · 2012 · 157 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

A Noncompetitive BACE1 Inhibitor TAK-070 Ameliorates Aβ Pathology and Behavioral Deficits in a Mouse Model of Alzheimer's Disease

Hiroaki Fukumoto, Hideki Takahashi, Naoki Tarui et al. · Journal of Neuroscience · 2010 · 129 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Design, Synthesis, and Biological Evaluation of Novel Investigational Nonapeptide KISS1R Agonists with Testosterone-Suppressive Activity

Taiji Asami, Naoki Nishizawa, Hisanori Matsui et al. · Journal of Medicinal Chemistry · 2013 · 49 citations · Full text

Medicine, Endocrinology, Pharmacology +17

Discovery, synthesis, and biological evaluation of novel pyrrole derivatives as highly selective potassium-competitive acid blockers

Haruyuki Nishida, Atsushi Hasuoka, Yasuyoshi Arikawa et al. · Bioorganic & Medicinal Chemistry · 2012 · 46 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Serum stability of selected decapeptide agonists of KISS1R using pseudopeptides

Taiji Asami, Naoki Nishizawa, Yoshihiro Ishibashi et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 33 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11