Haruyuki Nishida

1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine Monofumarate (TAK-438), a Novel and Potent Potassium-Competitive Acid Blocker for the Treatment of Acid-Related Diseases

Yasunobu Hori, Akio Imanishi, Jun Matsukawa et al. · Journal of Pharmacology and Experimental Therapeutics · 2010 · 199 citations

A Study Comparing the Antisecretory Effect of TAK-438, a Novel Potassium-Competitive Acid Blocker, with Lansoprazole in Animals

Yasunobu Hori, Jun Matsukawa, Toshiyuki Takeuchi et al. · Journal of Pharmacology and Experimental Therapeutics · 2011 · 169 citations

Discovery of a Novel Pyrrole Derivative 1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1<i>H</i>-pyrrol-3-yl]-<i>N</i>-methylmethanamine Fumarate (TAK-438) as a Potassium-Competitive Acid Blocker (P-CAB)

Yasuyoshi Arikawa, Haruyuki Nishida, Osamu Kurasawa et al. · Journal of Medicinal Chemistry · 2012 · 155 citations

Pharmaceutical Science, Bioorganic Chemistry, Potassium-competitive Acid Blocker +17

A comparative study on the modes of action of TAK-438, a novel potassium-competitive acid blocker, and lansoprazole in primary cultured rabbit gastric glands

Jun Matsukawa, Yasunobu Hori, Haruyuki Nishida et al. · Biochemical Pharmacology · 2011 · 100 citations

Biochemistry, Gastrointestinal Pharmacology, Medicine +6

Discovery, synthesis, and biological evaluation of novel pyrrole derivatives as highly selective potassium-competitive acid blockers

Haruyuki Nishida, Atsushi Hasuoka, Yasuyoshi Arikawa et al. · Bioorganic & Medicinal Chemistry · 2012 · 46 citations

Medicinal Chemistry, Biochemistry, Natural Sciences +9