Takako Naito

Pioglitazone, a peroxisome proliferator–activated receptor γ agonist, reduces the progression of experimental osteoarthritis in guinea pigs

Tetsuya Kobayashi, Kohei Notoya, Takako Naito et al. · Arthritis & Rheumatism · 2005 · 102 citations

Medicine, Orthopaedic Surgery, Pharmacology +17

Differential Contribution of Insulin and Amino Acids to the mTORC1-Autophagy Pathway in the Liver and Muscle

Takako Naito, Akiko Kuma, Noboru Mizushima · Journal of Biological Chemistry · 2013 · 85 citations · Full text

Life Sciences, Cell Biology, Physiology +16

Discovery of Novel, Highly Potent, and Selective Quinazoline-2-carboxamide-Based Matrix Metalloproteinase (MMP)-13 Inhibitors without a Zinc Binding Group Using a Structure-Based Design Approach

Hiroshi Nara, Kenjiro Sato, Takako Naito et al. · Journal of Medicinal Chemistry · 2014 · 59 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Discovery of Novel, Highly Potent, and Selective Matrix Metalloproteinase (MMP)-13 Inhibitors with a 1,2,4-Triazol-3-yl Moiety as a Zinc Binding Group Using a Structure-Based Design Approach

Hiroshi Nara, Akira Kaieda, Kenjiro Sato et al. · Journal of Medicinal Chemistry · 2016 · 56 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Thieno[2,3-d]pyrimidine-2-carboxamides bearing a carboxybenzene group at 5-position: Highly potent, selective, and orally available MMP-13 inhibitors interacting with the S1″ binding site

Hiroshi Nara, Kenjiro Sato, Takako Naito et al. · Bioorganic & Medicinal Chemistry · 2014 · 50 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13