Epigenetic PTEN Silencing in Malignant Melanomas without PTEN Mutation

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

Sandeep Robert Datta, Henryk Dudek, Xu Tao et al. · Cell · 1997 · 5.7K citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +11

<i>PTEN</i> , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

Jing Li, Clifford Yen, Danny Liaw et al. · Science · 1997 · 4.8K citations

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

Peter A. Steck, Mark A. Pershouse, Samar A. Jasser et al. · Nature Genetics · 1997 · 2.8K citations

Multiple Advanced Cancers, Tumor Biology, Chromosome 10Q23.3 +10

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

Danny Liaw, Deborah J. Marsh, Jing Li et al. · Nature Genetics · 1997 · 2.1K citations

Thyroid Cancer Syndrome, Genetics, Pathology +4

Inhibition of Cell Migration, Spreading, and Focal Adhesions by Tumor Suppressor PTEN

Masahito Tamura, Jianguo Gu, Kazue Matsumoto et al. · Science · 1998 · 1.2K citations

Cell Adhesion, Cytoskeleton, Cellular Physiology +17