Concepedia

Epigenetic Silencing

Epigenetic Silencing is a regulatory mechanism in molecular biology whereby gene expression is reversibly suppressed through covalent modifications of DNA or histone proteins without altering the underlying DNA sequence.

2K

Publications

171.1K

Citations

14.8K

Authors

2.6K

Institutions

Publications per year

2017–2026

597

Parents

Publications

2K

The Role of DNA Methylation in Mammalian Epigenetics

Peter A. Jones, Daiya Takai · Science · 2001 · 2.1K citations

, , +15

Lasting Epigenetic Influence of Early-Life Adversity on the BDNF Gene

Tania L. Roth, Farah D. Lubin, Adam J. Funk et al. · Biological Psychiatry · 2009 · 1.3K citations · Full text

, , +16

Vernalization-Mediated Epigenetic Silencing by a Long Intronic Noncoding RNA

Jae Bok Heo, Sibum Sung · Science · 2010 · 1.3K citations

, , +14

Dicer-deficient mouse embryonic stem cells are defective in differentiation and centromeric silencing

Chryssa Kanellopoulou, Stefan A. Muljo, Andrew L. Kung et al. · Genes & Development · 2005 · 1.2K citations · Full text

, , +17

Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas

Theo Knijnenburg, Linghua Wang, Michael T. Zimmermann et al. · Cell Reports · 2018 · 1.2K citations · Full text

, , +17

1–5 of 2K

Authors

14.8K

  1. CD
    Caroline Dean

    John Innes Centre, United Kingdom

    23 publications · 4.8K citations

    23

    h-index

  2. ME
    Manel Esteller

    Institut d'Investigació Biomédica de Bellvitge, Spain

    25 publications · 4.5K citations

    22

    h-index

  3. JG
    James G. Herman

    Johns Hopkins University, United States

    24 publications · 3.1K citations

    21

    h-index

  4. SB
    Stephen B. Baylin

    Johns Hopkins University, United States

    18 publications · 4.5K citations

    17

    h-index

  5. HS
    Hiromu Suzuki

    Sapporo Medical University, Japan

    17 publications · 2.2K citations

    16

    h-index

1–5 of 14.8K

Institutions

2.6K

  1. Johns Hopkins University

    Baltimore, United States

    43 h-index

    298 publications

    32.6K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    38 h-index

    148 publications

    49.1K citations

  3. Harvard University

    Cambridge, United States

    38 h-index

    224 publications

    51.9K citations

  4. Heidelberg University

    Heidelberg, Germany

    35 h-index

    219 publications

    12.7K citations

  5. National Cancer Institute

    Bethesda, United States

    33 h-index

    148 publications

    19.6K citations

  6. Chinese University of Hong Kong

    Hong Kong, Hong Kong

    31 h-index

    266 publications

    24.4K citations

  7. The University of Texas MD Anderson Cancer Center

    Houston, United States

    31 h-index

    155 publications

    39.6K citations

  8. Chinese Academy of Sciences

    Beijing, China

    29 h-index

    169 publications

    15K citations

1–8 of 2.6K

Venues

  1. Cancer Research

    88 publications · 11.9K citations

    65

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 66 publications · 11.4K citations

    51

    h-index

  3. PLoS ONE

    84 publications · 4.6K citations

    41

    h-index

  4. Oncogene

    47 publications · 4.2K citations

    38

    h-index

  5. Nature Communications

    44 publications · 4.2K citations

    36

    h-index

1–5