Mast cells are essential intermediaries in regulatory T-cell tolerance

Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor <i>Foxp3 </i>

WanJun Chen, Wenwen Jin, Neil J. Hardegen et al. · The Journal of Experimental Medicine · 2003 · 4.6K citations · Full text

T-regulatory Cell, Immune Regulation, Immunology +18

Stimulation of CD25+CD4+ regulatory T cells through GITR breaks immunological self-tolerance

Jun Shimizu, Sayuri Yamazaki, Takeshi Takahashi et al. · Nature Immunology · 2002 · 1.7K citations

Autoimmune Disease, T-regulatory Cell, Immunology +8

Cutting Edge: Contact-Mediated Suppression by CD4+CD25+ Regulatory Cells Involves a Granzyme B-Dependent, Perforin-Independent Mechanism

David Gondek, Li‐Fan Lu, Sergio A. Quezada et al. · The Journal of Immunology · 2005 · 881 citations

Cd4+cd25- Effector Cell, Perforin-independent Mechanism, Molecular Regulation +22

IL-10 Is Required for Regulatory T Cells to Mediate Tolerance to Alloantigens In Vivo

Masaki Hara, Cherry Kingsley, Masanori Niimi et al. · The Journal of Immunology · 2001 · 778 citations · Full text

Mast Cell-Deficient W-sash c-kit Mutant KitW-sh/W-sh Mice as a Model for Investigating Mast Cell Biology in Vivo

Michele A. Grimbaldeston, Ching‐Cheng Chen, Adrian M. Piliponsky et al. · American Journal Of Pathology · 2005 · 580 citations · Full text

Knockout Mouse, Signal Transduction, Mast Cell Disorder +4