Concepedia

Tumor-specific intravenous gene delivery using oncolytic adenoviruses

Jinghui Zhan, Yi Gao, Wensheng Wang, Annie Shen, Amy Aspelund, Mandy Young, Sylvie Laquerre, Leonard Post, Yuqiao Shen

Cancer Gene Therapy · 2004 · 32 citations · 16 references

DOI

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References

16

An Adenovirus Mutant That Replicates Selectively in p53- Deficient Human Tumor Cells

James R. Bischoff, David H. Kirn, Angelica Williams et al. · Science · 1996 · 1.8K citations

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p53-Independent and -Dependent Requirements for E1B-55K in Adenovirus Type 5 Replication

Josephine N. Harada, Arnold Berk · Journal of Virology · 1999 · 259 citations · Full text

, , +14

Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015)

Stefan Ries, Christian Brandts, Alicia S. Chung et al. · Nature Medicine · 2000 · 191 citations

, , +14

Selectively replicating adenoviruses targeting deregulated E2F activity are potent, systemic antitumor agents

Leisa Johnson, Annie Shen, Larry Boyle et al. · Cancer Cell · 2002 · 190 citations · Full text

, , +12

E3 gene manipulations affect oncolytic adenovirus activity in immunocompetent tumor models

Yaohe Wang, Gunnel Halldén, Richard Hill et al. · Nature Biotechnology · 2003 · 161 citations

, , +16