Concepedia

Loss of p14ARF in tumor cells facilitates replication of the adenovirus mutant dl1520 (ONYX-015)

Stefan Ries, Christian Brandts, Alicia S. Chung, Carola Biederer, Byron Hann, Ettie M. Lipner, Frank McCormick, W. Michael Korn

Nature Medicine · 2000 · 191 citations · 31 references

DOI

Concepts

References

31

Requirement for p53 and p21 to Sustain G <sub>2</sub> Arrest After DNA Damage

Fred Bunz, Annie Dutriaux, Christoph Lengauer et al. · Science · 1998 · 2.8K citations

, , +17

An Adenovirus Mutant That Replicates Selectively in p53- Deficient Human Tumor Cells

James R. Bischoff, David H. Kirn, Angelica Williams et al. · Science · 1996 · 1.8K citations

, , +14

The Ink4a Tumor Suppressor Gene Product, p19Arf, Interacts with MDM2 and Neutralizes MDM2's Inhibition of p53

Jason H. Pomerantz, Nicole Schreiber‐Agus, Nanette J. Liégeois et al. · Cell · 1998 · 1.5K citations · Full text

, , +14

<i>p53</i> Status and the Efficacy of Cancer Therapy in Vivo

Scott W. Lowe, Stephan Bodis, Andrea I. McClatchey et al. · Science · 1994 · 1.5K citations

, , +17

mdm2 expression is induced by wild type p53 activity.

Yaacov Barak, T. Juven, Rebecca Haffner et al. · The EMBO Journal · 1993 · 1.3K citations · Full text

, , +8