Altered conformation of recombinant frontotemporal dementia-17 mutant tau proteins

Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17

Mike Hutton, Corinne Lendon, Patrizia Rizzu et al. · Nature · 1998 · 3.5K citations

Neurodegenerative Diseases, Mendelian Disorder, Genetic Disorder +8

Tau is a candidate gene for chromosome 17 frontotemporal dementia

Parvoneh Poorkaj, Thomas D. Bird, Ellen M. Wijsman et al. · Annals of Neurology · 1998 · 1.4K citations

Expression of separate isoforms of human tau protein: correlation with the tau pattern in brain and effects on tubulin polymerization.

Michel Goedert, Ross Jakes · The EMBO Journal · 1990 · 913 citations · Full text

Tau Pattern, Neurodegenerative Diseases, Protein Function +13

Altered microtubule organization in small-calibre axons of mice lacking tau protein

Atsushi Harada, K Oguchi, Shigeo Okabe et al. · Nature · 1994 · 755 citations

Tau Protein, Molecular Neuroscience, Protein Function +14

Alz-50 and MC-1, a new monoclonal antibody raised to paired helical filaments, recognize conformational epitopes on recombinant tau

Gregory A. Jicha, Robert Bowser, Imrana G. Kazam et al. · Journal of Neuroscience Research · 1997 · 557 citations