Parvoneh Poorkaj

Secreted amyloid β–protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease

Donalyn Scheuner, Christopher B. Eckman, M. Jensen et al. · Nature Medicine · 1996 · 2.6K citations

Life Sciences, Neurobiology, Neuroscience +16

Candidate Gene for the Chromosome 1 Familial Alzheimer's Disease Locus

Ephrat Levy‐Lahad, Wilma Wasco, Parvoneh Poorkaj et al. · Science · 1995 · 2.6K citations

Life Sciences, Genetics, Molecular Genetics +14

Tau is a candidate gene for chromosome 17 frontotemporal dementia

Parvoneh Poorkaj, Thomas D. Bird, Ellen M. Wijsman et al. · Annals of Neurology · 1998 · 1.4K citations

Life Sciences, Genetics, Neurology +13

Missense and silent tau gene mutations cause frontotemporal dementia with parkinsonism-chromosome 17 type, by affecting multiple alternative RNA splicing regulatory elements

Ian D’Souza, Parvoneh Poorkaj, Ming Hong et al. · Proceedings of the National Academy of Sciences · 1999 · 516 citations

Life Sciences, Genetics, Molecular Genetics +17

Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17

Lorraine N. Clark, Parvoneh Poorkaj, Daniel H. Geschwind et al. · Proceedings of the National Academy of Sciences · 1998 · 474 citations

Life Sciences, Genetics, Neurology +17