Concepedia

Skp2 Deletion Unmasks a p27 Safeguard that Blocks Tumorigenesis in the Absence of pRb and p53 Tumor Suppressors

Hongling Zhao, Frederick Bauzon, Hao Fu, Zhonglei Lu, Jinhua Cui, Keiko Nakayama, Keiichi I. Nakayama, Joseph Locker, Liang Zhu

Cancer Cell · 2013 · 80 citations · 41 references

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41

Definition of a consensus binding site for p53

Wafik S. El‐Deiry, Scott E. Kern, Jennifer A. Pietenpol et al. · Nature Genetics · 1992 · 2K citations

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An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer

Teresa A. Soucy, Peter G. Smith, Michael A. Milhollen et al. · Nature · 2009 · 2K citations

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Senescent fibroblasts promote epithelial cell growth and tumorigenesis: A link between cancer and aging

Ana Krtolica, Simona Parrinello, Stephen Lockett et al. · Proceedings of the National Academy of Sciences · 2001 · 1.7K citations · Full text

Mice Lacking p27 Display Increased Body Size, Multiple Organ Hyperplasia, Retinal Dysplasia, and Pituitary Tumors

Keiko Nakayama · Cell · 1996 · 1.6K citations · Full text

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Senescence surveillance of pre-malignant hepatocytes limits liver cancer development

Tae-Won Kang, Tetyana Yevsa, Norman Woller et al. · Nature · 2011 · 1.5K citations

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