Definition of a consensus binding site for p53

Mutations in the p53 gene occur in diverse human tumour types

Janice Nigro, Suzanne J. Baker, Antonette C. Preisinger et al. · Nature · 1989 · 2.8K citations · Full text

Tumor Biology, Somatic Variant, Tumor Heterogeneity +7

Identification of p53 as a Sequence-Specific DNA-Binding Protein

Scott E. Kern, Kenneth W. Kinzler, Arthur M. Bruskin et al. · Science · 1991 · 1.1K citations

Cancer Research, Oncogenic Agent, Natural Sciences +12

Presence of a Potent Transcription Activating Sequence in the p53 Protein

Stanley Fields, Sung Key Jang · Science · 1990 · 813 citations

Transcriptional Regulation, Cell Regulation, Yeast Gal4 +14

Transcriptional Activation by Wild-Type but Not Transforming Mutants of the p53 Anti-Oncogene

Loretta Raycroft, Hongyun Wu, Guillermina Lozano · Science · 1990 · 637 citations

Alter P53, Genetics, Molecular Biology +18

The GLI gene encodes a nuclear protein which binds specific sequences in the human genome.

K W Kinzler, B Vogelstein · Molecular and Cellular Biology · 1990 · 476 citations

Genetics, Genomic Mechanism, Molecular Biology +21