Concepedia

Discovery and structure–activity relationship studies of indole derivatives as liver X receptor (LXR) agonists

Farid Bakir, Sunil M. Kher, Madhavi Pannala, Norma Wilson, Trang Nguyen, Ila Sircar, Kei Takedomi, Chiaki Fukushima, James Zapf, Kui Xu,

Bioorganic & Medicinal Chemistry Letters · 2007 · 12 citations · 16 references

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16

Cholesterol and Bile Acid Metabolism Are Impaired in Mice Lacking the Nuclear Oxysterol Receptor LXRα

Daniel J. Peet, Stephen D. Turley, Wenzhen Ma et al. · Cell · 1998 · 1.4K citations · Full text

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LXR, a nuclear receptor that defines a distinct retinoid response pathway.

P J Willy, Kazuhiko Umesono, Estelita S. Ong et al. · Genes & Development · 1995 · 1.1K citations · Full text

, , +15

Structural requirements of ligands for the oxysterol liver X receptors LXRα and LXRβ

Bethany A. Janowski, Michael J. Grogan, Stacey A. Jones et al. · Proceedings of the National Academy of Sciences · 1999 · 926 citations

, , +16

Identification of a Nonsteroidal Liver X Receptor Agonist through Parallel Array Synthesis of Tertiary Amines

Jon L. Collins, Adam M. Fivush, Michael A. Watson et al. · Journal of Medicinal Chemistry · 2002 · 426 citations · Full text

, , +17

Antidiabetic Action of a Liver X Receptor Agonist Mediated By Inhibition of Hepatic Gluconeogenesis

Guoqing Cao, Liang Yu, Carol L. Broderick et al. · Journal of Biological Chemistry · 2003 · 291 citations · Full text

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