Ila Sircar

Structure-activity relationships of a series of 2-amino-4-thiazole-containing renin inhibitors

William C. Patt, Harriet W. Hamilton, Michael D. Taylor et al. · Journal of Medicinal Chemistry · 1992 · 371 citations · Full text

Medicinal Chemistry, Hypertension, Renin Inhibitors +13

Cardiotonic agents. 1. 4,5-Dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones: novel positive inotropic agents for the treatment of congestive heart failure

James A. Bristol, Ila Sircar, Walter H. Moos et al. · Journal of Medicinal Chemistry · 1984 · 150 citations · Full text

Heart Failure, Cardiovascular Pharmacology, Altmetric Attention Score +17

Cardiotonic agents. 2. Synthesis and structure-activity relationships of 4,5-dihydro-6-[4-(H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones: a new class of positive inotropic agents

Ila Sircar, Bradley L. Duell, George Bobowski et al. · Journal of Medicinal Chemistry · 1985 · 94 citations

Bioorganic Chemistry, Cardiovascular Pharmacology, Organic Chemistry +17

Cardiotonic agents. 8. Selective inhibitors of adenosine 3',5'-cyclic phosphate phosphodiesterase III. Elaboration of a five-point model for positive inotropic activity

Walter H. Moos, Christine Humblet, Ila Sircar et al. · Journal of Medicinal Chemistry · 1987 · 83 citations · Full text

Cardiotonic agents. 7. Inhibition of separated forms of cyclic nucleotide phosphodiesterase from guinea pig cardiac muscle by 4,5-dihydro-6-[4-(1H-imidazol-1-yl)phenyl]-3(2H)-pyridazinones and related compounds. Structure-activity relationships and correlation with in vivo positive inotropic activity

Ila Sircar, Ronald E. Weishaar, Dianne C. Kobylarz et al. · Journal of Medicinal Chemistry · 1987 · 66 citations · Full text

Cardiac Muscle, Pharmacotherapy, Chemical Biology +17