Promotion of Hras-induced squamous carcinomas by a polymorphic variant of the Patched gene in FVB mice

Mutations of the Human Homolog of Drosophila patched in the Nevoid Basal Cell Carcinoma Syndrome

Heidi Hahn, Carol Wicking, Peter G. Zaphiropoulos et al. · Cell · 1996 · 2K citations · Full text

Medicine, Genetics, Molecular Genetics +16

Human Homolog of <b> <i>patched</i> </b> , a Candidate Gene for the Basal Cell Nevus Syndrome

Ronald L. Johnson, Alana Rothman, Jingwu Xie et al. · Science · 1996 · 1.9K citations

Life Sciences, Genetics, Oncology +17

Altered Neural Cell Fates and Medulloblastoma in Mouse <i>patched</i> Mutants

Lisa V. Goodrich, Ljiljana Milenković, Kay M. Higgins et al. · Science · 1997 · 1.7K citations

Life Sciences, Genetics, Molecular Genetics +17

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine

Jussi Taipale, James Chen, Michael K. Cooper et al. · Nature · 2000 · 1.3K citations

Medicine, Cancer Biology, Oncology +9

Essential role for oncogenic Ras in tumour maintenance

Lynda Chin, Alice Tam, Jason H. Pomerantz et al. · Nature · 1999 · 872 citations

Medicine, Cancer Biology, Oncology +16