A cytosolic protein factor from the naked mole-rat activates proteasomes of other species and protects these from inhibition

Genome sequencing reveals insights into physiology and longevity of the naked mole rat

Eun Bae Kim, Xiaodong Fang, Alexey A. Fushan et al. · Nature · 2011 · 610 citations · Full text

Aging, Mammalian Physiology, Genetics +18

Proteasome Inhibitors in Cancer Therapy: Lessons from the First Decade

Robert Z. Orlowski, Deborah J. Kuhn · Clinical Cancer Research · 2008 · 582 citations

γ-Interferon and expression of MHC genes regulate peptide hydrolysis by proteasomes

Maria Gaczyńska, Kenneth L. Rock, Alfred L. Goldberg · Nature · 1993 · 571 citations

Mhc Genes, Protein Function, Protein Expression +8

A Small Molecule Inhibitor of Inducible Heat Shock Protein 70

Julia I-Ju Leu, Julia Pimkina, Amanda Frank et al. · Molecular Cell · 2009 · 442 citations · Full text

Protein Chemistry, Protein Function, Biochemistry +7

Importance of the Different Proteolytic Sites of the Proteasome and the Efficacy of Inhibitors Varies with the Protein Substrate

Alexei F. Kisselev, Alice Callard, Alfred L. Goldberg · Journal of Biological Chemistry · 2006 · 414 citations · Full text

Relative Importance, Proteasome, Cell Death +19