Concepedia

Nuclear/cytoplasmic localization of Akt activity in the cell cycle

Margit Rosner, Michaela Hanneder, Angelika Freilinger, Markus Hengstschläger

Amino Acids · 2007 · 22 citations · 16 references

DOI

Concepts

References

16

PKB/Akt phosphorylates p27, impairs nuclear import of p27 and opposes p27-mediated G1 arrest

Jiyong Liang, Judit Zubovitz, Teresa Petrocelli et al. · Nature Medicine · 2002 · 945 citations

, , +14

PKB/Akt mediates cell-cycle progression by phosphorylation of p27Kip1 at threonine 157 and modulation of its cellular localization

Incheol Shin, F. Michael Yakes, Federico Rojo et al. · Nature Medicine · 2002 · 786 citations

, , +16

Cytoplasmic relocalization and inhibition of the cyclin-dependent kinase inhibitor p27Kip1 by PKB/Akt-mediated phosphorylation in breast cancer

Giuseppe Viglietto, Maria Letizia Motti, Paola Bruni et al. · Nature Medicine · 2002 · 703 citations

, , +17

Akt-dependent Phosphorylation of p27Kip1Promotes Binding to 14-3-3 and Cytoplasmic Localization

Naoya Fujita, Saori Sato, Kazuhiro Katayama et al. · Journal of Biological Chemistry · 2002 · 353 citations · Full text

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A fraction of the mRNA 5' cap-binding protein, eukaryotic initiation factor 4E, localizes to the nucleus.

Flavio Lejbkowicz, C Goyer, A. Darveau et al. · Proceedings of the National Academy of Sciences · 1992 · 208 citations

, , +17