Concepedia

Dipeptidyl peptidase-4 inhibitor, vildagliptin, inhibits pancreatic beta cell apoptosis in association with its effects suppressing endoplasmic reticulum stress in db/db mice

Yanju Wu, Xin Guo, Chunjun Li, Daiqing Li, Jie Zhang, Yi‐Ping Yang, Yan Kong, Hang Guo, Demin Liu, Liming Chen

Metabolism · 2014 · 49 citations · 31 references

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References

31

β-Cell Deficit and Increased β-Cell Apoptosis in Humans With Type 2 Diabetes

Alexandra E. Butler, Juliette Janson, Susan Bonner‐Weir et al. · Diabetes · 2003 · 4K citations

CHOP is implicated in programmed cell death in response to impaired function of the endoplasmic reticulum

Hélène Zinszner, Masahiko Kuroda, X. Wang et al. · Genes & Development · 1998 · 2K citations · Full text

ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death

Jaeseok Han, Sung Hoon Back, Junguk Hur et al. · Nature Cell Biology · 2013 · 1.6K citations

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Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV.

Timothy J. Kieffer, Christopher H.S. McIntosh, Raymond A. Pederson · Endocrinology · 1995 · 1.1K citations

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TRB3, a novel ER stress‐inducible gene, is induced via ATF4–CHOP pathway and is involved in cell death

Nobumichi Ohoka, Satoshi Yoshii, Takayuki Hattori et al. · The EMBO Journal · 2005 · 992 citations · Full text