Concepedia

Upsides and Downsides of Reactive Oxygen Species for Cancer: The Roles of Reactive Oxygen Species in Tumorigenesis, Prevention, and Therapy

Subash C. Gupta, David Hevia, Sridevi Patchva, Byoungduck Park, Wonil Koh, Bharat B. Aggarwal

Antioxidants and Redox Signaling · 2011 · 720 citations · 257 references

DOIFull text

Open access

Abstract

the various mechanisms by which ROS mediate paradoxical effects are discussed in this article. The outstanding questions and future directions raised by our current understanding are discussed.

References

257

On Respiratory Impairment in Cancer Cells

Otto Warbürg · Science · 1956 · 3.1K citations

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Requirement for Generation of H <sub>2</sub> O <sub>2</sub> for Platelet-Derived Growth Factor Signal Transduction

Maitrayee Sundaresan, Zu-Xi Yu, Victor J. Ferrans et al. · Science · 1995 · 2.5K citations

Antioxidant Activity of Pomegranate Juice and Its Relationship with Phenolic Composition and Processing

María I. Gil, Francisco A. Tómas‐Barberán, Betty Hess-Pierce et al. · Journal of Agricultural and Food Chemistry · 2000 · 2.3K citations

The mitochondrial permeability transition pore and its role in cell death

Martin Crompton · Biochemical Journal · 1999 · 2.3K citations · Full text

H <sub>2</sub> O <sub>2</sub> , a Necessary Evil for Cell Signaling

Sue Goo Rhee · Science · 2006 · 2.1K citations

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