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The ΔF508 cystic fibrosis mutation impairs domain-domain interactions and arrests post-translational folding of CFTR

Protein FunctionMolecular PhysiologySignal TransductionMolecular RegulationProtein FoldingNatural SciencesMolecular BiologyCellular BiochemistryProtein GeneticsMedicineCell BiologyCell SignalingDomain-domain InteractionsPost-translational Folding