Murine lung cancer induces generalized T-cell exhaustion

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection

Shawn D. Blackburn, Haina Shin, W. Nicholas Haining et al. · Nature Immunology · 2008 · 2.1K citations · Full text

Life Sciences, Cell Biology, Immunology +16

Up-Regulation of PD-L1, IDO, and T _regs in the Melanoma Tumor Microenvironment Is Driven by CD8 ⁺ T Cells

Stefani Spranger, Robbert M. Spaapen, Yuanyuan Zha et al. · Science Translational Medicine · 2013 · 1.7K citations · Full text

Medicine, Immunology, Oncology +17

PD-1 expression by macrophages plays a pathologic role in altering microbial clearance and the innate inflammatory response to sepsis

Xin Huang, Fabienne Venet, Yvonne L. Wang et al. · Proceedings of the National Academy of Sciences · 2009 · 506 citations · Full text

Veterinary Medicine, Immunology, Pathobiology +17

The Epidemiology of Sepsis in Patients With Malignancy

Pajman A. Danai, Marc Moss, David M. Mannino et al. · CHEST Journal · 2006 · 468 citations

Veterinary Medicine, Infectious Diseases, Oncology +10

Coexpression of PD-1, 2B4, CD160 and KLRG1 on Exhausted HCV-Specific CD8+ T Cells Is Linked to Antigen Recognition and T Cell Differentiation

Bertram Bengsch, Bianca Seigel, Marianne Ruhl et al. · PLoS Pathogens · 2010 · 370 citations · Full text

Life Sciences, Immunology, Infectious Diseases +17