Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock

Pratyusha Mandal, Yanjun Feng, John D. Lyons, +21

Immunity

InflammationAnti-inflammatoryDrive Tissue DamageMedicineApoptosis +8

CXCR4 blockade decreases CD4+ T cell exhaustion and improves survival in a murine model of polymicrobial sepsis

Kimberly M. Ramonell, Wenxiao Zhang, Annette Hadley, +7

PLoS ONE

ImmunologyImmune RegulationImmunologic MechanismCd4 T Cell ResponsesImmunotherapy +17

Murine lung cancer induces generalized T-cell exhaustion

Rohit Mittal, Ching‐Wen Chen, John D. Lyons, +4

Journal of Surgical Research

Cancer ImmunosurveillanceT-cell ExhaustionImmunologyBronchial NeoplasmLung Cancer +3

Epidermal Growth Factor Improves Intestinal Integrity and Survival in Murine Sepsis Following Chronic Alcohol Ingestion

Nathan J. Klingensmith, Benyam P. Yoseph, Zhe Liang, +6

Shock

Acute Lung InjuryEpidermal Growth FactorIntestinal IntegrityHuman GrowthGastrointestinal Pharmacology +17

Modern Management of Penetrating Tracheal Injuries

John D. Lyons, David V. Feliciano, Amy D. Wyrzykowski, +1

The American Surgeon

TracheobronchitisSpinal Cord InjuryTracheal RepairTracheal StenosisMedicine +12

Attrition of memory CD8 T cells during sepsis requires LFA-1

Mara A. Serbanescu, Kimberly M. Ramonell, Annette Hadley, +7

Journal of Leukocyte Biology

Thyroidectomy Is Optimal Treatment for Graves’ Disease

David V. Feliciano, John D. Lyons

Journal of the American College of Surgeons

Regulators of Intestinal Epithelial Migration in Sepsis

Mei Meng, Nathan J. Klingensmith, Zhe Liang, +5

Shock

InflammationGut IntegrityDysbiosisMucosal ImmunologyIntestinal Epithelial Migration +11

Chronic Alcohol Ingestion Worsens Survival and Alters Gut Epithelial Apoptosis and CD8+ T Cell Function After Pseudomonas Aeruginosa Pneumonia-Induced Sepsis

Nathan J. Klingensmith, Katherine Fay, John D. Lyons, +7

Shock

InflammationMucosal ImmunologyMicrobial PathogensDisease PathophysiologyMedicine +11

Junctional adhesion molecule-A deletion increases phagocytosis and improves survival in a murine model of sepsis

Nathan J. Klingensmith, Katherine Fay, David A. Swift, +10

JCI Insight

Adaptive Immune SystemCell AdhesionInnate Immune SystemImmunologyImmune Regulation +23