JTT‐130, a novel intestine‐specific inhibitor of microsomal triglyceride transfer protein, suppresses high fat diet‐induced obesity and glucose intolerance in Sprague‐Dawley rats

Abstract

JTT-130 suppresses high fat diet-induced obesity and glucose intolerance with suppression of food intake and fat absorption and could be useful for prevention and treatment of obesity and obesity-related insulin resistance.