Concepedia

Stepwise Activation of BAX and BAK by tBID, BIM, and PUMA Initiates Mitochondrial Apoptosis

Hyungjin Kim, Ho-Chou Tu, Decheng Ren, Osamu Takeuchi, John Jeffers, Gerard P. Zambetti, James J. Hsieh, Emily H. Cheng

Molecular Cell · 2009 · 579 citations · 44 references

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References

44

Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death

Michael C. Wei, Wei‐Xing Zong, Emily H. Cheng et al. · Science · 2001 · 3.9K citations · Full text

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The expanding role of mitochondria in apoptosis.

X. Wang · PubMed · 2001 · 2.4K citations

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Movement of Bax from the Cytosol to Mitochondria during Apoptosis

Keith G. Wolter, Yi‐Te Hsu, Carolyn L. Smith et al. · The Journal of Cell Biology · 1997 · 1.8K citations · Full text

, , +15

BCL-2, BCL-XL Sequester BH3 Domain-Only Molecules Preventing BAX- and BAK-Mediated Mitochondrial Apoptosis

Emily H. Cheng, Michael C. Wei, Solly Weiler et al. · Molecular Cell · 2001 · 1.7K citations · Full text

, , +10

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

Anthony Letai, Michael C. Bassik, Loren D. Walensky et al. · Cancer Cell · 2002 · 1.6K citations · Full text

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