Oncolytic adenovirus-mediated transfer of the antisense chk2 selectively inhibits tumor growth in vitro and in vivo

Liver Transplantation for the Treatment of Small Hepatocellular Carcinomas in Patients with Cirrhosis

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An Adenovirus Mutant That Replicates Selectively in p53- Deficient Human Tumor Cells

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Medicine, Cancer Biology, Oncology +14

A controlled trial of intratumoral ONYX-015, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer

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Medicine, Oncology, Chemotherapy +8

Hepatic Arterial Infusion of Chemotherapy after Resection of Hepatic Metastases from Colorectal Cancer

Nancy E. Kemeny, Ying Huang, Alfred M. Cohen et al. · New England Journal of Medicine · 1999 · 960 citations · Full text

Medicine, Oncology, Pharmacotherapy +17

ONYX-015, an E1B gene-attenuated adenovirus, causes tumor-specific cytolysis and antitumoral efficacy that can be augmented by standard chemotherapeutic agents

Carla Heise, Adam Sampson-Johannes, Angelica Williams et al. · Nature Medicine · 1997 · 947 citations

Medicine, Oncology, Pharmacology +13