Concepedia

Viral Engineering

Viral Engineering is a methodological approach in oncolytic virus immunotherapy that involves the deliberate modification of viral genomes to enhance tumor selectivity, immune activation, and therapeutic efficacy while preserving viral replication capacity.

767

Publications

40.2K

Citations

4.4K

Authors

963

Institutions

Publications per year

2017–2026

173

Parents

Publications

767

Experimental Therapy of Human Glioma by Means of a Genetically Engineered Virus Mutant

Robert L. Martuza, Amy Malick, James M. Markert et al. · Science · 1991 · 1K citations

, , +14

SARS-CoV-2 D614G variant exhibits efficient replication ex vivo and transmission in vivo

Yixuan J. Hou, S. Chiba, Peter Halfmann et al. · Science · 2020 · 1K citations · Full text

, , +16

Construction and Manipulation of a New Kaposi's Sarcoma-Associated Herpesvirus Bacterial Artificial Chromosome Clone

Kevin Brulois, Heesoon Chang, Amy Si-Ying Lee et al. · Journal of Virology · 2012 · 377 citations · Full text

, , +17

<i>In planta</i> engineering of viral RNA replicons: Efficient assembly by recombination of DNA modules delivered by <i>Agrobacterium</i>

Sylvestre Marillonnet, Anatoli Giritch, Mario Gils et al. · Proceedings of the National Academy of Sciences · 2004 · 364 citations · Full text

, , +17

Systemic cancer therapy with a tumor-selective vaccinia virus mutant lacking thymidine kinase and vaccinia growth factor genes.

J. Andrea McCart, Jerrold M. Ward, Yun Hu et al. · PubMed · 2001 · 362 citations

, , +17

1–5 of 767

Authors

4.4K

  1. SJ
    Stephen J. Russell

    Mayo Clinic, United States

    22 publications · 1.2K citations

    18

    h-index

  2. YF
    Yuman Fong

    Memorial Sloan Kettering Cancer Center, United States

    18 publications · 629 citations

    15

    h-index

  3. JC
    John C. Bell

    University of Ottawa, Canada

    15 publications · 1.5K citations

    15

    h-index

  4. GY
    G. Yancey Gillespie

    University of Alabama at Birmingham, United States

    13 publications · 1.1K citations

    12

    h-index

  5. AH
    Akseli Hemminki

    University of Helsinki, Finland

    12 publications · 823 citations

    12

    h-index

1–5 of 4.4K

Institutions

963

  1. Harvard University

    Cambridge, United States

    22 h-index

    119 publications

    10K citations

  2. University of Alabama at Birmingham

    Birmingham, United States

    20 h-index

    122 publications

    9.7K citations

  3. Mayo Clinic

    Rochester, United States

    20 h-index

    110 publications

    5.5K citations

  4. Baylor College of Medicine

    Houston, United States

    18 h-index

    102 publications

    6.9K citations

  5. Mayo Clinic in Arizona

    Scottsdale, United States

    18 h-index

    75 publications

    5K citations

  6. Massachusetts General Hospital

    Boston, United States

    17 h-index

    80 publications

    9.3K citations

  7. German Cancer Research Center

    Heidelberg, Germany

    17 h-index

    95 publications

    3.2K citations

  8. Memorial Sloan Kettering Cancer Center

    New York, United States

    17 h-index

    101 publications

    3.8K citations

1–8 of 963

Venues

  1. Journal of Virology

    JVI · 77 publications · 4.8K citations

    38

    h-index

  2. Molecular Therapy

    47 publications · 3.3K citations

    32

    h-index

  3. Gene Therapy

    43 publications · 2K citations

    28

    h-index

  4. PubMed

    Repository · 42 publications · 3.2K citations

    28

    h-index

  5. Human Gene Therapy

    37 publications · 1.8K citations

    26

    h-index

1–5