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Effect of <i>SLCO1B1</i> genetic polymorphism on the pharmacokinetics of nateglinide

DOIFull Paper Access

100

Citations

17

References

2006

Year

Wei Zhang, Yijing He, Chun‐Ting Han, Zhaoqian Liu, Qing Li, Lan Fan, Zhi‐Rong Tan, Wei‐Xia Zhang, Bangning Yu, Dan Wang,
British Journal of Clinical Pharmacology

Abstract

Our results suggest that OATP1B1-mediated hepatic uptake of nateglinide may be the prior step for its metabolism and elimination. SLCO1B1521T > C SNP might play an important role in the pharmacokinetics of nateglinide.

References

YearCitations

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