Yoshihisa Shitara

Contribution of OATP2 (OATP1B1) and OATP8 (OATP1B3) to the Hepatic Uptake of Pitavastatin in Humans

Masaru Hirano, Kazuya Maeda, Yoshihisa Shitara et al. · Journal of Pharmacology and Experimental Therapeutics · 2004 · 442 citations

Pharmacy, Biochemistry, Pharmacology +16

Gemfibrozil and Its Glucuronide Inhibit the Organic Anion Transporting Polypeptide 2 (OATP2/OATP1B1:SLC21A6)-Mediated Hepatic Uptake and CYP2C8-Mediated Metabolism of Cerivastatin: Analysis of the Mechanism of the Clinically Relevant Drug-Drug Interaction between Cerivastatin and Gemfibrozil

Yoshihisa Shitara, Masaru Hirano, Hitoshi Sato et al. · Journal of Pharmacology and Experimental Therapeutics · 2004 · 405 citations

Medicine, Pharmacokinetics, Pharmacology +17

Physiologically Based Pharmacokinetic Modeling to Predict Transporter-Mediated Clearance and Distribution of Pravastatin in Humans

Takao Watanabe, Hiroyuki Kusuhara, Kazuya Maeda et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 350 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Inhibition of Transporter-Mediated Hepatic Uptake as a Mechanism for Drug-Drug Interaction between Cerivastatin and Cyclosporin A

Yoshihisa Shitara, Tomoo Itoh, Hitoshi Sato et al. · Journal of Pharmacology and Experimental Therapeutics · 2003 · 340 citations · Full text

Medicine, Biochemistry, Pharmacology +17

DRUG-DRUG INTERACTION BETWEEN PITAVASTATIN AND VARIOUS DRUGS VIA OATP1B1

Masaru Hirano, Kazuya Maeda, Yoshihisa Shitara et al. · Drug Metabolism and Disposition · 2006 · 301 citations

Medicine, Biochemistry, Pharmacology +15