PEGylated helper-dependent adenoviral vector expressing human Apo A-I for gene therapy in LDLR-deficient mice

Effect of potentially modifiable risk factors associated with myocardial infarction in 52 countries (the INTERHEART study): case-control study

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Medicine, Cardiology, Internal Medicine +15

Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery.

S Ishibashi, Mark S. Brown, Joseph L. Goldstein et al. · Journal of Clinical Investigation · 1993 · 1.6K citations · Full text

Life Sciences, Molecular Genetics, Pharmacology +16

Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer

Steven E. Raper, Narendra Chirmule, Frank S. Lee et al. · Molecular Genetics and Metabolism · 2003 · 1.5K citations

Life Sciences, Immunology, Molecular Genetics +14

Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity

Gudrun Schiedner, Núria Morral, Robin J. Parks et al. · Nature Genetics · 1998 · 646 citations

Life Sciences, Biotechnology, Molecular Biology +16

Quantitation of atherosclerosis in murine models: correlation between lesions in the aortic origin and in the entire aorta, and differences in the extent of lesions between sexes in LDL receptor-deficient and apolipoprotein E-deficient mice

Rajendra K. Tangirala, Edward M. Rubin, Wulf Palinski · Journal of Lipid Research · 1995 · 516 citations · Full text

Life Sciences, Physiology, Inflammation +12