Gudrun Schiedner

Genomic DNA transfer with a high-capacity adenovirus vector results in improved in vivo gene expression and decreased toxicity

Gudrun Schiedner, Núria Morral, Robin J. Parks et al. · Nature Genetics · 1998 · 646 citations

Vivo Gene Expression, In Vivo Gene Therapy, Natural Sciences +13

Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: Toward realistic long-term neurological gene therapy for chronic diseases

Clare E. Thomas, Gudrun Schiedner, Stefan Kochanek et al. · Proceedings of the National Academy of Sciences · 2000 · 253 citations · Full text

Viral Pathogenesis, Immunology, Immunotherapy +22

Adenovirus-mediated regulable target gene expression <i>in vivo</i>

Mark Burcin, Gudrun Schiedner, Stefan Kochanek et al. · Proceedings of the National Academy of Sciences · 1999 · 249 citations

Signal Transduction, Protein Expression, Signaling Pathway +13

High Doses of a Helper-Dependent Adenoviral Vector Yield Supraphysiological Levels of <i>α</i> ₁ -Antitrypsin with Negligible Toxicity

Núria Morral, Robin J. Parks, Heshan Zhou et al. · Human Gene Therapy · 1998 · 246 citations

Efficient Transformation of Primary Human Amniocytes by E1 Functions of Ad5: Generation of New Cell Lines for Adenoviral Vector Production

Gudrun Schiedner, Sabine Hertel, Stefan Kochanek · Human Gene Therapy · 2000 · 179 citations

Viral Replication, Primary Human Amniocytes, Synthetic Virology +19