Clare E. Thomas

Rapid Uncoating of Vector Genomes Is the Key toEfficient Liver Transduction with Pseudotyped Adeno-Associated VirusVectors

Clare E. Thomas, Theresa A. Storm, Zan Huang et al. · Journal of Virology · 2004 · 347 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +14

Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: Toward realistic long-term neurological gene therapy for chronic diseases

Clare E. Thomas, Gudrun Schiedner, Stefan Kochanek et al. · Proceedings of the National Academy of Sciences · 2000 · 253 citations

Life Sciences, Neurobiology, Neuroscience +13

Preclinical in vivo evaluation of pseudotyped adeno-associated virus vectors for liver gene therapy

Dirk Grimm, Shangzhen Zhou, Hiroyuki Nakai et al. · Blood · 2003 · 207 citations · Full text

Life Sciences, Biotechnology, Molecular Biology +12

Acute Direct Adenoviral Vector Cytotoxicity and Chronic, but Not Acute, Inflammatory Responses Correlate with Decreased Vector-Mediated Transgene Expression in the Brain

Clare E. Thomas, Darren Birkett, Ijeoma Anozie et al. · Molecular Therapy · 2001 · 173 citations · Full text

Life Sciences, Neurobiology, Neuroscience +15

Preexisting Antiadenoviral Immunity Is Not a Barrier to Efficient and Stable Transduction of the Brain, Mediated by Novel High-Capacity Adenovirus Vectors

Clare E. Thomas, Gudrun Schiedner, Stefan Kochanek et al. · Human Gene Therapy · 2001 · 99 citations

Life Sciences, Neurobiology, Neuroscience +15