Concepedia

Expression of survivin in astrocytic tumors

Yoshinori Kajiwara, Fumiyuki Yamasaki, Seiji Hama, Kaita Yahara, Hiroyuki Yoshioka, Kazuhiko Sugiyama, Kazunori Arita, Kaoru Kurisu

Cancer · 2003 · 146 citations · 41 references

DOI

Abstract

Survivin expression in astrocytic tumors varies with histologic malignancy and may play an important role in the oncogenesis and progression of astrocytic tumors. These data suggest that survivin has great potential as a therapeutic target in astrocytic tumors.

References

41

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

Grazia Ambrosini, Colette Adida, Dario C. Altieri · Nature Medicine · 1997 · 3.2K citations

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Mutations in the p53 gene occur in diverse human tumour types

Janice Nigro, Suzanne J. Baker, Antonette C. Preisinger et al. · Nature · 1989 · 2.8K citations · Full text

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Control of apoptosis and mitotic spindle checkpoint by survivin

Fengzhi Li, Grazia Ambrosini, Emily Chu et al. · Nature · 1998 · 1.9K citations

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Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

Towia A. Libermann, Harris R. Nusbaum, Nissim Razon et al. · Nature · 1985 · 1.5K citations

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Overexpression of the EGF Receptor and <i>p53</i> Mutations are Mutually Exclusive in the Evolution of Primary and Secondary Glioblastomas

Kunihiko Watanabe, Osamu Tachibana, Kazufumi Sato et al. · Brain Pathology · 1996 · 732 citations · Full text