Control of apoptosis and mitotic spindle checkpoint by survivin

A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma

Grazia Ambrosini, Colette Adida, Dario C. Altieri · Nature Medicine · 1997 · 3.2K citations

Tumor Biology, Oncogenic Agent, Novel Anti-apoptosis Gene +8

X-linked IAP is a direct inhibitor of cell-death proteases

Quinn L. Deveraux, Ryōsuke Takahashi, Guy S. Salvesen et al. · Nature · 1997 · 1.9K citations

Protein Function, Apoptosis, Autophagy +5

Mutations of mitotic checkpoint genes in human cancers

Daniel P. Cahill, Christoph Lengauer, Jian Yu et al. · Nature · 1998 · 1.5K citations

Somatic Variant, Cancer Genomics, Cancer Genetics +5

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases

Natalie Roy · The EMBO Journal · 1997 · 1.3K citations · Full text

Protein Function, Signal Transduction, Specific Caspases +12

IAP-family protein survivin inhibits caspase activity and apoptosis induced by Fas (CD95), Bax, caspases, and anticancer drugs.

Ingo Tamm, Yi Wang, Edward A. Sausville et al. · PubMed · 1998 · 1.3K citations

Apoptosis Protein, Apoptosis, Cell Death +18