Bio-functional micelles self-assembled from a folate-conjugated block copolymer for targeted intracellular delivery of anticancer drugs

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Yasuhiro Matsumura, Hiroshi Maeda · PubMed · 1986 · 6.8K citations

Pathology, Cancer Biology, Cancer Chemotherapy +17

Block copolymer micelles for drug delivery: design, characterization and biological significance

Kazunori Kataoka, Atsushi Harada, Yukio Nagasaki · Advanced Drug Delivery Reviews · 2001 · 3.5K citations

Block Co-polymers, Engineering, Polymer-drug Conjugate +11

Solution Properties of Poly(N-isopropylacrylamide)

M. Heskins, J. E. Guillet · Journal of Macromolecular Science Part A - Chemistry · 1968 · 3.1K citations

Materials Science, Polymer Material, Engineering +14

Thermo-responsive drug delivery from polymeric micelles constructed using block copolymers of poly(N-isopropylacrylamide) and poly(butylmethacrylate)

Joo Eun Chung, M. Yokoyama, Masayuki Yamato et al. · Journal of Controlled Release · 1999 · 591 citations

Engineering, Block Copolymers, Polymer-drug Conjugate +9

Critical micellization phenomena in block polyelectrolyte solutions

Irina Astafieva, Xing Zhong, Adi Eisenberg · Macromolecules · 1993 · 574 citations

Engineering, Altmetric Attention Score, Polyelectrolyte Gel +19