Concepedia

Antigen-specific human antibodies from mice comprising four distinct genetic modifications

Nils Lönberg, Lisa D. Taylor, Fiona Harding, Mary Trounstine, Kay M. Higgins, Stephen R. Schramm, Chiung-Chi Kuo, Roshanak Mashayekh, Kathryn Wymore, James McCabe,

Nature · 1994 · 392 citations · 16 references

DOI

Concepts

References

16

Continuous cultures of fused cells secreting antibody of predefined specificity

Georges Köhler, César Milstein · Nature · 1975 · 17.2K citations

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A Randomized Clinical Trial of OKT3 Monoclonal Antibody for Acute Rejection of Cadaveric Renal Transplants

New England Journal of Medicine · 1985 · 713 citations

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Immunoglobulin gene rearrangement in B cell deficient mice generated by targeted deletion of the J<sub>H</sub> locus

Jianzhu Chen, Mary Trounstine, Frederick W. Alt et al. · International Immunology · 1993 · 399 citations

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A second B cell-specific enhancer 3' of the immunoglobulin heavy-chain locus

Sven Pettersson, Graham P. Cook, Marianne Brüggemann et al. · Nature · 1990 · 220 citations

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The immunoglobulin kappa locus contains a second, stronger B‐cell‐specific enhancer which is located downstream of the constant region.

Kerstin B. Meyer, Michael S. Neuberger · The EMBO Journal · 1989 · 213 citations · Full text

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