ESM-1 silencing decreased cell survival, migration, and invasion and modulated cell cycle progression in hepatocellular carcinoma

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

Hong Sun, Ralf Lesche, Daming Li et al. · Proceedings of the National Academy of Sciences · 1999 · 821 citations

Life Sciences, Cell Biology, Molecular Biology +17

PTEN/MMAC1/TEP1 suppresses the tumorigenicity and induces G ₁ cell cycle arrest in human glioblastoma cells

Daming Li, Hong Sun · Proceedings of the National Academy of Sciences · 1998 · 512 citations · Full text

Medicine, Cancer Biology, Oncology +17

The phosphoinositol phosphatase activity of PTEN mediates a serum-sensitive G1 growth arrest in glioma cells.

Frank B. Furnari, Hongyi Huang, Webster K. Cavenee · PubMed · 1998 · 400 citations

Life Sciences, Molecular Biology, Oncology +17

ESM-1 Is a Novel Human Endothelial Cell-specific Molecule Expressed in Lung and Regulated by Cytokines

Philippe Lassalle, Sophie Molet, Anne Janin et al. · Journal of Biological Chemistry · 1996 · 387 citations · Full text

Life Sciences, Molecular Biology, Cell Signaling +10

Tumor Suppressor Pten Inhibits Nuclear Accumulation of β-Catenin and T Cell/Lymphoid Enhancer Factor 1–Mediated Transcriptional Activation

Sujata Persad, Armelle A. Troussard, Timothy R. McPhee et al. · The Journal of Cell Biology · 2001 · 296 citations · Full text

Medicine, Molecular Biology, Oncology +17